Structure and properties of ICG-COOH Indocyanine green ICG-carboxylic group

ICG-COOH (IndoCyanine Green-Carboxylic Acid) is a compound derived from indocyanine green (IndoCyanine Green) and has the following structure and properties:

Structure:

The chemical structure of ICG-COOH is composed of an indocyanine green molecule and a carboxylic acid group. It is an organic molecule containing multiple ring structures which contain the same indole and alkyl chains as indocyanine green. In the carboxylic acid group of the molecule, the carboxyl group is attached to the main part of the molecule through a single bond.

Nature:

1. Solubility: ICG-COOH is a water-soluble compound that can form stable solutions in water. This makes ICG-COOH widely used in biomedical fields such as drug delivery and bio-imaging.

2. Fluorescent properties: ICG-COOH has fluorescent properties with strong absorption and emission spectra in the near infrared region (NIR). This gives ICG-COOH important potential for applications in bio-imaging, photodynamic therapy, and other applications.

3. Biocompatibility: ICG-COOH has good biocompatibility and does not cause significant toxicity or immune reactions. This makes ICG-COOH an ideal biomarker and drug carrier.

4. Photothermal Conversion Capability: ICG-COOH can absorb light energy and convert it into heat energy, producing a photothermal effect. This allows ICG-COOH to be used in photodynamic therapy to destroy tumor cells or treat other diseases.

In summary, ICG-COOH is a compound with water solubility, fluorescent properties, biocompatibility and photothermal conversion ability. It has a wide range of potential applications in biomedical fields, such as drug delivery, bioimaging and photodynamic therapy.