Structure and properties of CY7-COOH Cyanine 7-carboxylic group

Cyanine7-COOH is a Cyanine7 dye with a carboxyl group (-COOH). Its chemical structure is shown below:

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H3C--CH=CH--N(CH3)2--C6H4--CH=CH--C6H4--N(CH3)2--CH=CH--C6H4--CH=CH--C6H4--COOH

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Cyanine 7-COOH has several characteristics and properties:

1. Fluorescent properties: Cyanine 7-COOH has strong fluorescent properties, with a maximum excitation wavelength of about 750 nm and a maximum emission wavelength of about 773 nm, which makes it emit fluorescence in the near-infrared spectral range, which is favorable for optical imaging and analysis in living organisms.

2. Solubility: Cyanine 7-COOH has good solubility in some organic solvents (e.g., methanol, dimethyl sulfoxide, etc.) and water. This makes it has a better application prospect in biomolecular labeling and analysis.

3. Reactivity: The carboxyl group (-COOH) on Cyanine 7-COOH is reactive and can be used for covalent coupling or chemical reactions with other molecules. For example, it can be combined with amino compounds or amino acids through carboxylate activation reactions to prepare specific markers or probes.

4. Stability: Cyanine 7-COOH has good stability and can be stored for long periods of time and maintain its fluorescent properties under appropriate conditions. It is also highly stable to light and heat, making it suitable for long term use in optical imaging and analysis.

In conclusion, Cyanine7-COOH is a Cyanine7 dye with a carboxyl group, which has strong fluorescent properties, good solubility and stability. It can be used in near-infrared optical imaging and analysis, as well as coupling with other molecules through chemical reactions for biomolecular labeling and probe preparation.