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  5. DOSPA;282533-23-7
cationic liposome
Brand YUSI
English name DOSPA;N-(2-(2,5-Bis((3-aminopropyl)amino)pentanamido)ethyl)-N,N-dimethyl-2,3-bis((Z)-octadec-9-en-1-yloxy)propan-1-aminium chloride tetrahydrochloride;
Chinese alias DOSPA;282533-23-7
Technical index ≥95%
CAS 282533-23-7 Product number
Molecular formula C54H115Cl5N6O3 Molecular weight 1073.8g/mol
Product number Specifications Price Stock
  • Quantity:
  • Unit Price:
    0.00RMB

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  • Product information

Product Structure:

DOSPA;N-(2-(2,5-Bis((3-aminopropyl)amino)pentanamido)ethyl)-N,N-dimethyl-2,3-bis((Z)-octadec-9-en-1-yloxy)propan-1-aminium chloride tetrahydrochloride


Size :

1g(Specifications can be customized)


Product details:

Solubility: DOSPA is soluble in organic solvents such as chloroform and methanol, which are commonly used for lipid film preparation. It is also soluble in aqueous solutions at pH values above its pKa (around 7). 

Stability: DOSPA liposomes are generally stable under physiological conditions. However, they can be sensitive to factors such as temperature, pH, and presence of divalent cations. It is important to optimize the formulation conditions to ensure the stability of DOSPA liposomes during storage and administration.

Storage conditions: DOSPA liposomes should be stored at a temperature below their phase transition temperature, which is typically around 40-45°C. Storage at room temperature or below is recommended to prevent lipid degradation and maintain the integrity of the liposomes. It is also important to protect DOSPA liposomes from light exposure as it can affect their stability.

 




Description:

DOSPA, which stands for Dioleoylphosphatidylserine, is a type of cationic liposome. Cationic liposomes are lipid-based nanoparticles that have a positive charge on their surface. DOSPA is commonly used in biomedical research and drug delivery systems. 

DOSPA liposomes are formed by combining DOSPA lipid with other lipid components, such as cholesterol, to create a stable and versatile delivery system. The positive charge on the surface of DOSPA liposomes allows for efficient interaction with negatively charged molecules, such as nucleic acids, proteins, and drugs. 

DOSPA liposomes have been widely studied for their potential applications in gene therapy, where they can efficiently deliver genetic material, such as DNA or RNA, into target cells. The positive charge of DOSPA liposomes promotes their binding to negatively charged cell membranes, facilitating cellular uptake and intracellular delivery of the genetic material.




Storage conditions:

Store at - 20 ℃. Avoid frequent thawing and freezing.

Note: The products sold by our company are only used for scientific research, not for human experiments or human treatment.


Based on the business model of independent research and development, production and sales integration, the company's products have obvious price advantages compared with similar products on the market. In addition, we also provide professional product customization services.


For other products, please contact us:

Telephone: 023-62795528

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Dospa


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