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Cholesterol-PEG-NHS,CLS-PEG-NHS、 Cholesterol (polyethylene glycol) Succinimidyl Carboxyl Methyl ester
1g（Specifications can be customized）
Properties: Based on different molecular weights, it is white / almost white solid or viscous liquid.
Solvent: chloroform, dichloromethane, DMSO, water and other conventional organic solvents.
Stability: cold storage, avoid repeated freezing and thawing.
Molecular weight (PEG): 2000, 3400, 5000, other molecular weights can be customized.
Active group: active ester (NHS)
In order to ensure the stability of the product, please note that the package can only be opened for use after constant temperature drying!
CLS-PEG-NHS is a kind of PEG derivative with different bifunctional groups. Cholesterol is the basic material of cell membrane and liposome. It is also an indispensable material for animal tissues and cells. It not only participates in the formation of cell membrane, but also is the raw material for the synthesis of bile acid, vitamin D and steroids. Cholesterol can regulate the fluidity of phospholipid bilayer membrane, reduce membrane permeability and drug leakage. At the same time, it can maintain the flexibility of lipid membrane and enhance the ability of liposome vesicles to resist the changes of external conditions. It also has a protective effect on the oxidation of phospholipids. Active ester (NHS) ph7-8.5 reacts with primary amine group to form stable amide bond. Peg conjugated cholesterol has better water solubility. Peg conjugated cholesterol derivatives can be used for cell membrane imaging, liposomes and drug delivery.
Handling and use:
CLS-PEG-NHS Attention should be paid to temperature difference and air humidity to prevent moisture absorption. In the reaction as far as possible in the inert gas protection.
CLS-PEG-NHS It needs to be stored at - 20 ℃ in dry condition under inert gas protection.
Note: The products sold by our company are only used for scientific research, not for human experiments or human treatment.
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